لَّا يَمَسُّهُ إِلَّا الْمُطَهَّرُونَ

This verse refers to the Quran in its preserved form (the original in Allah's presence), stating that only the purified beings (angels) touch it there. However, it also establishes a principle about approaching the Quran with purity and reverence. The "purified" (mutahharun) primarily refers to angels who are inherently pure, but the principle extends to humans approaching the Quran with physical and spiritual cleanliness. This teaches that the Quran deserves to be approached with utmost respect and purity, that physical cleanliness when handling the Quran shows proper reverence, that spiritual purity enhances one's ability to benefit from the Quran, and that the Quran's sacred nature requires appropriate conduct when engaging with it. The verse encourages believers to maintain both physical and spiritual cleanliness when reading or handling the Quran, reflecting the reverence due to Allah's word.